matrixyl 3000 (microcollagen pentapeptide)

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Matrixyl 3000 is a combination of the two peptides, palmitoyl oligopeptide and palmitoyl tetrapeptide-7, and a proven micro-collagen fragment designed to help stimulate new collagen, minimizing the appearance of fine lines and wrinkles.

Palmitoyl oligopeptide is one of the two active ingredients in Matrixyl 3000. It consists of a short chain of three amino acids connected to palmitic acid. Palmitic acid is a fatty acid added to improve the peptide's oil solubility and thus skin penetration. Palmitoyl oligopeptide is a fragment of type I collagen molecule and is believed to serve as a biological indicator of increased degradation of the skin matrix. Indeed, when collagen is degraded, more of its small fragments get created in the body, including palmitoyl oligopeptide. Furthermore, it is believed to stimulate the feedback loop triggering the synthesis of new collagen as well as other components of the skin matrix. When the key skin matrix-producing cells (fibroblasts) detect increased levels of palmitoyl oligopeptide, they "assume" that the skin matrix is being lost at a higher rate and begin synthesizing it more vigorously. Thus, it is intended to stimulate skin matrix replenishment via topical application, leading to wrinkle reduction, skin firming and other benefits.

Palmitoyl tetrapeptide-7 consists of a short chain of four amino acids connected to palmitic acid. Palmitic acid is a fatty acid added to improve the peptide's oil solubility and thus skin penetration. Palmitoyl tetrapeptide-7 works by reducing the production of interleukin-6 (IL-6) by the the key skin cells, keratinocytes and fibroblasts. IL-6 is a molecule that promotes inflammation, which, in turn, leads to faster degradation of the skin matrix and thus contributes to the development of wrinkles and loss of skin firmness and elasticity. By reducing the levels of IL-6 and possibly other inflammation mediators, palmitoyl tetrapeptide-7 is thought to slow down the degradation of the skin matrix and may also stimulate its replenishment.

Click here for the scientific research and results of the effectiveness of Matrixyl3000.

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